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Fincher: We start with the source material. We start with the book and that is what the book described. I didnt feel there was any need to put a frame around it. We wanted to make sureone of the most important things was how you meat out the moment in her personification where she gets to be happy. One of the things we were very particular about was when she meets Miriam Wu in the bar. We wanted that to be a moment of happiness. There are two times that you see her smile in the entire movie and one of them is when is she gets the attention of Elodie [Yung] and Elodie comes over to kind of say, Why are you here alone? I thought that was important. I also think that Salanders sexuality is less of a ambidextrous thing than it is something that she has to act on. I think the tragedy is that friction is not a problem for her

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An on-ramp to a dead end A study of nearly 40,000 people conducted over a four-year period as part of The Ohio State Universitys Million Hearts educational program identified nonsmokers, current regular smokers and those who said they were social smokers, meaning they didnt have a cigarette every day

Keller-Hamilton, whose center produces federally funded research to guide the FDAs tobacco industry regulations