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So while the original indica plant, indigenous to the Middle East, might have differed genetically and chemically-speaking to its sativa cousin from central Asia, things are now too mixed up for there to be a clear distinction, says Myles

However, if they quit, withdrawal symptoms emerge first and then craving results

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An additional factor that may explain why former smokers who ceased all nicotine use had higher odds of hypertension than those who switched to e-cigarettes is post-cessation weight gain

Perhaps the most cited concern is nicotine, the stimulant that makes cigarettes and vapes addictive