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Real-world use patterns, in which users puff on the waterpipe differently to the puffing regimen prescribed by the International Organization for Standardization (ISO) standard used in this study, may give rise to different absolute and relative aerosol toxicant yields, as has been reported both for waterpipe 48,49,50 and other tobacco/nicotine products 51

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According to the 2002 National Youth Tobacco Survey, cigars were the second most popular tobacco product among young people