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Once cigarette smoke enters the bloodstream, its harmful chemicals spread throughout the body, causing damage to multiple organs and systems

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Regarding the specific mechanism of renal function affected by smoking, the possible mechanisms are as follows: smoking can cause chronic endothelial dysfunction, oxidative stress, and hardening of glomeruli (31, 32), while in vivo research evidence shows that nicotine inhalation causes the proliferation of mesangial cells (33)

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