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Similarly, ceramide-LC3B (Microtubule-associated proteins 1A/1B light chain 3B) interactions have been implicated in lethal mitophagy instances in acute myeloid leukemia (AML), head and neck squamous cell carcinoma (HNSCC), and aged T cells [86]

10.1186/s12967-017-1306-5 [DOI] [PMC free article] [PubMed] [Google Scholar] Liu Y.-B., Hong J.-R., Jiang N., Jin L., Zhong W.-J., Zhang C.-Y., et al

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Without treatment, the fibres that help to transmit visual information from the optic nerve to our brains start to deteriorate, interrupting the flow of information and causing permanent blindness