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Methods Our research group has previously published a detailed description of the study protocol (NCT02247908) that we pilot tested in July and August 2014 with 56 adult smokers in North Carolina (Supplement 1)

Raphael Mechoulam and a team of researchers from The Hebrew University Medical Faculty in Israel

Its worth noting here that unlike many NRT options like patches or gum, e-cigarettes arent actually recognised by Governments in many countries as a means of reducing/quitting smoking

"This one came out, and the phone started ringing, literally." 10

It takes only about 10 seconds for nicotine to reach your brain after you inhale, so the reward is almost immediate