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Due to these vascular effects, blood vessel walls thicken and blood platelet stickiness is increased, which raises the risk of clot formation and the subsequent development of heart attacks and strokes.Numerous chemicals found in cigarettes have the potential to cause harmful DNA alterations that lead to the development of cancer

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The largest global tobacco industry companies colloquially grouped together as Big Tobacco often highlighted the difference between tobacco and classic addictive drugs

Accessed 11/13/2008, [ Carpenter CM, Connolly GN, Ayo-Yusuf O, Wayne GF: Developing smokeless tobacco products for smokers: an examination of tobacco industry documents

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