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In 2004, more than 5,500 of the original subjects responded to a follow-up postal survey and more than 1,000 underwent additional lung function testing between 2006 and 2008

Thorndike, MD, MPH, suggested a third scenario as being more likely for young users: Teenagers who vape may never switch to smoking but will become nicotine-dependent adults who vape. With novel vaping technologies that deliver high doses of nicotine efficiently and cleanly, the gateway theory may be outdated, wrote Thorndike, with Massachusetts General Hospital and Harvard Medical School in Boston