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The statistical approach used complete case analysis to ensure that models were fitted on a complete and comparable study population, and multiple imputation for missing data was deemed unsuitable

This corresponds with the smoke-free generation approach, which has become clearly embedded in Dutch society and national policy-making 17

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If the difference between a need and a desire is that a need can be satisfied, then the need for nicotine was unique because it could go on being satisfied all of the time: twenty, forty, even a hundred times a day

Second, there is variation in prices across clusters, referred to as variation in between-cluster prices