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After reviewing 78 completed studies, including 40 randomized controlled trials, representing 22,052 participants, researchers found high-certainty evidence that e-cigarettes with nicotine increased quit rates compared to nicotine replacement therapy and that they were also more effective than other cessation methods

Li G, Chan YL, Sukjamnong S, Anwer AG, Vindin H, Padula M et al (2019) A mitochondrial specific antioxidant reverses metabolic dysfunction and fatty liver induced by maternal cigarette smoke in mice