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Moreover, cigarette smoke induced an increase in Treg cells through GPR15, which contributed to mitigating its impact on UC in mouse models

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Application of Conventional Tobacco Smoke Tracers and Biomarkers In the absence of validated tracers and biomarkers that have specificity for THS, the current best approach in exposure assessment studies is to use conventional tracers, such as tobacco alkaloids and TSNAs, and biomarkers, such as nicotine, other tobacco alkaloids, and TSNA metabolites