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Given the involvement of differential mtDNA methylation in various diseases and the critical involvement of mitochondrial dysfunction in COPD [30], the aim of the current study was to investigate in airway epithelial cells, whether the CSE-induced dysfunction in mitochondria and changes in mitochondrial gene expression are related to changes in mtDNA methylation

But the Royal College of Physicians has previously called for the devices to be made more widely available, arguing smokers should be moved on to safer substitutes such as e-cigarettes to supplement therapeutic approaches using nicotine patches and gum