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McAdam K, Eldridge A, Fearon IM, Liu C, Manson A, Murphy J, et al

An alternative hypothesis is depicted on the right, in which inhalation of chemicals common in e-cigarette aerosols (propylene glycol, glycerin, nicotine, or THC) alters the inflammatory state of the lungs, including changing alveolar macrophages to a proinflammatory phenotype with the release of inflammatory cytokines (indicated by yellow circles), such that a second hit causes a pathologic inflammatory response

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(b) Surbl et al., A new isoreticular class of metal- organic frameworks with the MIL-88 topology , Chem